[HTML][HTML] Studies on apigenin and its biological and pharmacological activity in brain disorders

V Kumar, S Kundu - Advanced Pharmaceutical Bulletin, 2022 - ncbi.nlm.nih.gov
… by attenuating the expression of COX-2 and iNOS. At the … ROS generation; obstructing p38
MAPK, MAPKAP kinase-2, … in a copper-mediated β-amyloid neurotoxicity cell model of AD. …

NEUROPROTECTIVE AND ANTICANCER BIOACTIVITY OF APIGENIN

F KAZAK - Functional Foods and Nutraceuticals: Bioactive …, 2022 - books.google.com
Apigenin attenuates coppermediated β-amyloid neurotoxicity through antioxidation,
mitochondrion protection and MAPK signal inactivation in an AD cell model. Brain Res. 2013; 1492: …

Pharmacological and molecular insight on the cardioprotective role of apigenin

SD Thomas, NK Jha, SK Jha, B Sadek, S Ojha - Nutrients, 2023 - mdpi.com
Apigenin attenuated brain damage and improved neuronal … inactivation, attributing protection
against cellular damage. … cell survival while reciprocating p38/JNK/p53 MAP kinase and …

Neuroprotective effect of artichoke-based nanoformulation in sporadic Alzheimer's disease mouse model: focus on antioxidant, anti-inflammatory, and amyloidogenic …

HAS El-Nashar, H Abbas, M Zewail, MH Noureldin… - Pharmaceuticals, 2022 - mdpi.com
apigenin was reported to attenuate copper-mediated β-amyloid-induced neurotoxicity via its
antioxidant … microglial inactivation and over-expression of brain-derived neurotrophic factor (…

Therapeutic applications of apigenin and its derivatives: micro and nano aspects

H Javid, S Ahmadi, E Mohamadian - Micro Nano Bio Aspects, 2023 - mnba-journal.com
Apigenin attenuates copper-mediated β-amyloid neurotoxicity through antioxidation,
mitochondrion protection and MAPK signal inactivation in an AD cell model. Brain Research. …

Medicine-food herbs against alzheimer's disease: A review of their traditional functional features, substance basis, clinical practices and mechanisms of action

P Guo, B Zhang, J Zhao, C Wang, Z Wang, A Liu, G Du - Molecules, 2022 - mdpi.com
… that DGBXT protected β-amyloid-induced cell death by altering the … of quercetin in attenuating
AD are antioxidant activities, mainly … Another study showed that apigenin could exert …

Apigenin alleviates neuroinflammation in a mouse model of Parkinson's disease

GF Yarim, F Kazak, M Yarim, M Sozmen… - International Journal …, 2022 - Taylor & Francis
Apigenin administration attenuated MPTP-induced … disease model induced with copper-mediated
beta-amyloid … exerts a neuroprotective effect by maintaining mitochondrial function, …

Impact of mitochondrial aldehyde dehydrogenase 2 on cognitive impairment in the AD model mouse

Y Yang, W Chen, X Wang, W Ge - Acta Biochimica et Biophysica …, 2021 - academic.oup.com
… viability, the effects of which were attenuated by the ALDH2 activator Alda-1 (… to elucidate
the protective effect of ALDH2 on AD. … The inactivation of mitochondrial key enzymes leads to …

Insights Into the Role of Copper in Neurodegenerative Diseases and the Therapeutic Potential of Natural Compounds

G Zhong, X Wang, J Li, Z Xie, Q Wu… - Current …, 2024 - ingentaconnect.com
Apigenin antagonized copper-mediatedneurotoxicity in … the p38 MAPK/JNK signaling
pathway, vitegnoside attenuatedattenuated copper-induced neurotoxicity in SH-SY5Y cells by …

Nutraceuticals in neurodegenerative diseases

V Boccardi, C Tinarelli, P Mecocci - 2020 - books.rsc.org
… The anti-oxidant activity can attenuate neurotoxicity and … Apigenin can be found in common
vegetables and fruits such … angiogenesis in the formation of β-amyloid plaques. Although the …